Pharmacology of Severe Sepsis and Septic Shock

Welcome to the inaugural module of ALiEM CAPSULES. The focus of this module is to review the pharmacotherapy of some of the sickest patients encountered in the emergency department. The learning objectives for this module are to:

  • Review the pharmacologic profile of medications utilized in the resuscitation of patients with severe sepsis and septic shock
  • Understand the core principles in the approach to antimicrobial therapy for septic patients
  • Design individualized medication therapy regimens for septic patients
  • Apply knowledge of evidence-based practices to a patient case
Role Team Member Background
Authors Jill Logan, PharmD, BCPS
Emergency Medicine Pharmacist, University of Maryland Medical Center
Adam Spaulding, PharmD, BCPS
Emergency Medicine Pharmacist, Boston Medical Center
PharmD Reviewer Craig Cocchio, PharmD, BCPS
Emergency Medicine Pharmacist, Trinity Mother Frances Hospital
Physician Reviewer Michael Winters, MD, FAAEM, FACEP
Associate Professor of Emergency Medicine and Internal Medicine, University of Maryland
Creator and Lead Editor Bryan Hayes, PharmD, FAACT
Emergency Medicine Pharmacist, Clinical Associate Professor; University of Maryland

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  6. The ProCESS Investigators. A Randomized Trial of Protocol-Based Care for Early Septic Shock. N Eng J Med. 2014;370;1683-93.
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