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Welcome to the first of several ALiEM Capsules modules discussing infectious diseases. The focus of this module is to introduce some foundational concepts in the appropriate use of antimicrobial agents in the emergency department. Later Capsules modules will delve more into the treatment of specific conditions (e.g., pneumonia).

Learning Objectives

  1. Describe the risks and benefits of antimicrobials for various infectious etiologies encountered in emergency medicine (sepsis, pharyngitis, urinary tract infections, skin and soft tissue infections)
  2. Identify which antimicrobials may be safely used in patients with a history of drug allergies (e.g., penicillin allergy)
  3. Describe the evidence behind techniques to optimize antimicrobial pharmacokinetics (e.g., vancomycin loading doses and prolonged infusions of beta-lactam antibiotics)
Authors Affiliation Twitter
Meghan Groth, PharmD, BCPS Emergency Medicine Pharmacist, UMass Memorial Medical Center @EMPharmgirl
Paul Takamoto, PharmD Emergency Medicine Pharmacist, University of California, San Francisco @ptakpharm
Reviewers Affiliation Twitter
PharmD Reviewer: Michelle Hines, PharmD Food and Drug Administration @mEDPharmD
PharmD Reviewer: Zlatan Coralic, PharmD, BCPS Emergency Medicine Pharmacist, University of California, San Francisco @ZEDPharm
Expert Reviewer: Emily Heil, PharmD, BCPS-AQ ID Infectious Diseases Pharmacist, University of Maryland Medical Center @emilylheil
Editors Affiliation Twitter
Emily Wiener, PharmD Emergency Medicine Pharmacist, Baltimore Washington Medical Center @PharmdEMily
Xander Miller P4 Pharmacy Student, Northeastern University/Pharmacy Intern, Massachusetts General Hospital @XanderBOS
Lead Editor: Bryan Hayes, PharmD, FAACT, FASHP Emergency Medicine Pharmacist, Massachusetts General Hospital @PharmERToxGuy